The Placebo Effect Can Work Even When You Know It's a Placebo
Psychology

The Placebo Effect Can Work Even When You Know It's a Placebo

Most people assume the placebo effect only works if you don't know you're taking a fake pill. But research from Harvard Medical School found that patients who were openly told they were taking placebos — 'open-label placebos' — still reported significant relief from irritable bowel syndrome compared to a control group. The brain's expectation of healing can trigger real biological changes, even with full knowledge.

Source

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940593/

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Published
April 8, 2026
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